Status:
UNKNOWN
Percutaneous Treatment of Partial Anomalous Pulmonary Venous Drainage
Lead Sponsor:
The Leeds Teaching Hospitals NHS Trust
Conditions:
Partial Anomalous Pulmonary Venous Connection
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Partial anomalous pulmonary venous drainage (PAPVD) occurs in around 1 in every 1000 people. Blood from part of the lung returns to the wrong side of the heart, causing the heart to stretch. This caus...
Detailed Description
PAPVD has been reported in 0.2% of the population undergoing CT scans and in 0.4 - 0.7% of the population in autopsy studies. They can be associated with superior sinus venosus atrial septal defects o...
Eligibility Criteria
Inclusion
- Haemodynamically \& Functionally significant PAPVD (all of the following)
- Right heart dilated on trans thoracic echo
- cardiac MRI Qp:Qs ≥ 1.3:1, and right ventricular to left ventricular volume (RV:LV) ratio ≥ 1.5:1
- Maximal oxygen consumption (VO2 max) on cardiopulmonary exercise testing \< 85% predicted
- Normal pulmonary artery pressure
- No contra-indication to pulmonary artery intervention procedure under general anaesthetic
- Able to give informed consent
Exclusion
- Contra-indication to cardiac MRI
- Not able to give informed consent
- Contra-indication to pulmonary artery intervention under general anaesthetic
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2024
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT06048679
Start Date
January 1 2024
End Date
September 1 2024
Last Update
September 21 2023
Active Locations (1)
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1
Leeds Teaching Hospitals NHS Trust
Leeds, West Yorkshire, United Kingdom, LS1 3EX