Status:
COMPLETED
CRP/Albumin Ratio as a Predictive Inflammatory Marker for Postoperative SIRS and/or Sepsis
Lead Sponsor:
Ain Shams University
Conditions:
Crp
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this observational study is to determine the value of CRP/Albumin Ratio as an inflammatory marker for predicting the development of postoperative Systemic Inflammatory Response Syndrome an...
Detailed Description
The development of postoperative Systemic Inflammatory Response Syndrome (SIRS) or Sepsis is a very serious complication that has been associated with high morbidity, mortality, and increased length o...
Eligibility Criteria
Inclusion
- Patients classified by American Society of Anesthesiologists physical status (ASA) as I to III.
- Both sex.
- Aged ≥ 18 years old.
- Polytraumatized patients (fulfilling the 'New Berlin definition' of Polytrauma patient which includes Abbreviated Injury Scale (AIS) ≥3 for two or more different body regions with one or more of the following five physiological variables: Disturbed level of consciousness, hypotension, coagulopathy, acidosis and age \>70y).
- Admitted to Intensive Care Unit preoperatively or postoperatively. • Surgical intervention within 48 hours of the onset of Trauma.
Exclusion
- Patients who used immunosuppressive therapy and chemotherapy.
- Patients with known hematological disorders or malignancy.
- Patients with known liver cirrhosis classified as Child- Pugh C ( serum Albumin \< 2.8 mg/dl or International Normalized Ratio \> 2.2 ) (Tsoris , et al.,2023) or liver cell failure.
- Patients receiving Albumin Supplementation during the period of the study.
- Age \< 18y.
Key Trial Info
Start Date :
December 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 30 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06050759
Start Date
December 1 2023
End Date
December 30 2024
Last Update
April 2 2025
Active Locations (1)
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1
AinShams University Specialized Hospital
Cairo, Abbasia, Egypt