Status:

ENROLLING_BY_INVITATION

Investigating How the Brain Processes Different Experiences

Lead Sponsor:

Brown University

Collaborating Sponsors:

Dartmouth College

Tiny Blue Dot Foundation

Conditions:

Anxiety

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to test the efficacy of an app-based program in reducing anxiety and exploring associated changes in brain activity.

Detailed Description

The main question\[s\] it aims to answer are: PRIMARY AIM: Confirm that the conscious experience of open/closed correlates with P/PCC activation/deactivation. SECONDARY AIM: Determine if changes in ...

Eligibility Criteria

Inclusion

  • 18 - 65 years
  • Able to travel to Brown University for research assessment
  • Able to speak English because all study activities will be conducted in English.
  • GAD-7 ≥ 10
  • Owns a smartphone

Exclusion

  • If using psychotropic medication - not on a stable dosage at least 6 weeks
  • As needed (i.e., prn) benzodiazepine use
  • Psychotic disorder (e.g., bipolar disorder, schizophrenia, schizoaffective disorder, psychosis)
  • MRI contraindications
  • Claustrophobia
  • Recreational drug use past 2 weeks
  • Alcohol abuse
  • Pregnancy or plans to become pregnant
  • Cohabiting with a study participant
  • Weight ≥ 300 lbs (due to inability to fit in scanner)

Key Trial Info

Start Date :

October 5 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2025

Estimated Enrollment :

125 Patients enrolled

Trial Details

Trial ID

NCT06051084

Start Date

October 5 2023

End Date

March 31 2025

Last Update

March 15 2024

Active Locations (1)

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Brown University

Providence, Rhode Island, United States, 02903