Status:
COMPLETED
Dexmedetomidine vs Fentanyl on Time to Extubation in Patients Undergoing Laparoscopic Sleeve Gastrectomy
Lead Sponsor:
Helwan University
Conditions:
Dexmedetomidine
Fentanyl
Eligibility:
All Genders
20-50 years
Phase:
NA
Brief Summary
This study aims to compare the efficacy of dexmedetomidine versus fentanyl during general anesthesia for patients with morbid obesity undergoing laparoscopic sleeve gastrectomy.
Detailed Description
The use of opioids in surgeries for patients with morbid obesity is controversial since they are known for having ventilatory depressing effects. Therefore, alternative analgesics are needed to improv...
Eligibility Criteria
Inclusion
- Age from 20 to 50 years old.
- Both sexes.
- American Standards Association (ASA) physical status II - III.
- Body Mass Index (BMI) ≥ 35 kg/m2.
Exclusion
- Allergy to α2 -adrenergic agonist.
- History of cardiac disease (uncontrolled hypertensive patient with blood pressure above 140/90, implanted pacemaker, poor cardiac function (ejection fraction\< 50%), history of myocardial infarction, cerebral stroke, transient ischemic attack, or coronary artery disease with or without stents.
- Neuromuscular disease, liver disease (coagulopathy INR\>1.5 or platelet count \<100.000/μl), renal impairment (serum creatinine \>1.2mg/dl, serum K \>5.5mmol/l).
- Opioid medication within 24 hours before the operation.
- Respiratory diseases as COPD, uncontrolled asthmatic patients.
Key Trial Info
Start Date :
May 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 15 2023
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT06052111
Start Date
May 15 2021
End Date
May 15 2023
Last Update
September 25 2023
Active Locations (1)
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1
Helwan University
Helwan, Cairo Governorate, Egypt