Status:

UNKNOWN

Influence of Vasopressors on Anti-Xa Activity in Critically Ill Patients

Lead Sponsor:

Medical University of Gdansk

Conditions:

Critical Illness

Thrombosis

Eligibility:

All Genders

18-85 years

Brief Summary

Critically ill patients require antithrombotic prophylaxis. At the same time, majority of them is receiving various vasopressors. The aim of the study is to determine whether there is a difference in ...

Eligibility Criteria

Inclusion

  • Circulatory failure
  • Supported by continuous infusion of noradrenaline or noradrenaline and argipressin
  • Receiving subcutaneous dalteparin for the prevention of venous thromboembolism.

Exclusion

  • Contraindications for dalteparin
  • Severe coagulopathy
  • Acute or subacute bacterial endocarditis
  • Pregnant women
  • BMI (body mass index) \> 30kg/m2
  • Chronic kidney disease with eGFR (estimated glomerular filtration rate) \< 30 ml/min/1.73 m2
  • Renal replacement therapy
  • The patient died within 52 hours of starting VTE (venous thromboembolism) prophylaxis with dalteparin

Key Trial Info

Start Date :

May 15 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2024

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06055907

Start Date

May 15 2023

End Date

September 1 2024

Last Update

September 28 2023

Active Locations (1)

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Medical University of Gdańsk - Departament of Anesthesiology and Intensive Care

Gdansk, Poland, 80-214