Status:
RECRUITING
Microbes and Respiratory Illnesses
Lead Sponsor:
University of Wisconsin, Madison
Collaborating Sponsors:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Virus
Asthma
Eligibility:
All Genders
4-12 years
Brief Summary
This study is called the Microbes and Respiratory Illnesses (MARI) Study. Children growing up on farms are exposed to many types of microbes that could be beneficial. It is thought that increased expo...
Detailed Description
Respiratory viruses, most notably rhinoviruses (RV), commonly infect school-age children during the month of September and are a well-known exposure for asthma exacerbations. Allergic sensitization is...
Eligibility Criteria
Inclusion
- Participant and/or parent guardian must be able to understand and provide informed consent
- Children ages 4-12 years of age
- Cohort 1: Family is self-identified as Traditional agrarian (TA) Community member
- Cohort 2: Madison-area children with parental report of doctor-diagnosed asthma
- Cohort 3: Madison-area children with no history of asthma by parental report
- Cohort 4: Madison-area children who have an active respiratory illness
Exclusion
- Inability or unwillingness of a participant to give written informed consent or comply with study protocol
- Chronic sinusitis (frequent sinus infections)
- Plans to move out of the area before completing the study
- Past or current medical problems or findings from physical examination or laboratory testing that are not listed above, which, in the opinion of the investigator, may pose additional risks from participation in the study, may interfere with the participant's ability to comply with study requirements or that may impact the quality or interpretation of the data obtained from the study
- Enrolled family member
Key Trial Info
Start Date :
October 18 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
350 Patients enrolled
Trial Details
Trial ID
NCT06059027
Start Date
October 18 2023
End Date
December 1 2027
Last Update
May 15 2025
Active Locations (1)
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1
University of Wisconsin School of Medicine and Public Health
Madison, Wisconsin, United States, 53792