Status:

COMPLETED

Effectiveness of Conservative Treatment in Patients With Thoracic and Lumbar Fractures Without Neurological Deficit

Lead Sponsor:

Sklifosovsky Institute of Emergency Care

Conditions:

Thoracic Spine Fracture

Lumbar; Spine, Fracture

Eligibility:

All Genders

18-65 years

Brief Summary

The goal of this observational study is to compare the long-term clinical outcomes of two treatment methods (conservative therapy and surgical treatment) in patients with fractures of the thoracic and...

Detailed Description

The main objectives of the upcoming study include: * to conduct a retrospective analysis of the surgical treatment outcomes in patients with thoracic or lumbar vertebral fractures; * to assess the im...

Eligibility Criteria

Inclusion

  • Patients aged 18 to 65 years.
  • Isolated fracture of a single thoracic or lumbar vertebra, classified as type A2 or A3 according to the AOSpine classification.
  • Absence of clinical evidence of nerve root or spinal cord compression at the injury level.
  • Degree of spinal canal space narrowing less than 50% based on CT scans.
  • Informed consent to participate in the study.

Exclusion

  • Sagittal imbalance (Type 4 by C. Barrey).
  • Vertebral bone density at the injury level less than 100 HU or osteoporosis exceeding grade 3 in vertebral bodies, pelvic bones, and limbs.
  • Previous spinal surgeries.
  • Anesthesia risk of 4 or 5 according to ASA.
  • Acute exacerbation and decompensation of somatic diseases.
  • Malignant tumors at any site.
  • Systemic connective tissue disorders.
  • Cognitive impairments hindering patient communication.
  • Floating and mural thrombosis, regardless of location.
  • Newly identified and uncorrectable cardiac rhythm disorders.
  • Dizziness.
  • Consequences of a previous acute cerebrovascular event.
  • Pregnancy at any stage.
  • Acute infectious diseases.
  • History of fractures of the pelvis, lower limbs, or vertebral bodies.
  • Congenital spinal and limb disorders.
  • Any conditions contraindicating physiotherapeutic procedures.
  • Patient refusal to participate in the study.
  • Inability to participate in follow-up examinations for one year after the injury.
  • Participation in other clinical trials.
  • Absence of a signed informed voluntary consent for medical interventions and processing of personal data or personal data processing.

Key Trial Info

Start Date :

November 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 29 2025

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06059820

Start Date

November 1 2023

End Date

September 29 2025

Last Update

October 3 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Sklifosovsky Research Institute for Emergency Medicine

Moscow, Russia, 107045

2

Moscow Scientific and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine

Moscow, Russia, 111674