Status:
RECRUITING
Biomarkers of Reaction To HIIT Exercise
Lead Sponsor:
VA Office of Research and Development
Collaborating Sponsors:
Atlanta VA Medical Center
Conditions:
Stroke
Stroke Rehabilitation
Eligibility:
All Genders
18-89 years
Phase:
NA
Brief Summary
Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy. However, some individuals may not respond to HIIT even ...
Detailed Description
Most chronic subcortical stroke survivors have difficulty walking, but few predictors can help identify if a patient will respond to an exercise regimen and improve their function. To enhance precisio...
Eligibility Criteria
Inclusion
- chronic left or right subcortical stroke as defined by 6 months or more after a cardiovascular accident
- lower extremity motor impairment due to stroke that causes a walking speed of less than 0.6 m/s during a 10m walk
- Veteran status
Exclusion
- MRI contraindications, including implanted cardiac pacemakers and severe claustrophobia
- any neurodegenerative condition other than stroke that may lead to lower extremity impairment
- a visual or auditory impairment that may hinder study procedures
- any medical condition that would preclude participation in a physical exercise intervention program
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT06059872
Start Date
January 1 2024
End Date
December 1 2027
Last Update
April 1 2025
Active Locations (1)
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1
Atlanta VA Medical and Rehab Center, Decatur, GA
Decatur, Georgia, United States, 30033-4004