Status:
UNKNOWN
Augmentation of Interpersonal Psychotherapy With High-Definition Transcranial Direct Current Stimulation for Adolescent Depression
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Conditions:
Depressive Disorder
Eligibility:
All Genders
12-18 years
Phase:
NA
Brief Summary
Depression is among the most prevalent psychiatric disorders, with an upward trend in its manifestation in younger individuals. In contrast to adult depression, adolescent depression often presents wi...
Eligibility Criteria
Inclusion
- Sign a written informed consent form, willing to participate in the study and accept treatment (patients under 18 years of age need to obtain the consent of their parents or legal guardians);
- Age between 12 and 18 years;
- Right-handed;
- Han ethnicity;
- Meet the DSM-5 diagnostic criteria for depression;
- HAMD-24≥20;
- Understand written language and able to complete questionnaires;
- First-episode depression patients who have never received any treatment or relapse depression patients, have not taken any psychotropic drugs in the past 2 weeks, have not received systematic psychological or physical therapy.
Exclusion
- Exclusion criteria for tDCS: (1) Patients with metal implants in the body; those with metal implants such as titanium or magnetic devices (including aneurysm clips); (2) Patients with implanted devices such as cardiac pacemakers, deep brain stimulators (DBS); (3) Patients with intracranial hypertension, skull defects, or tumors; (4) Patients with unstable vital signs such as severe cardiac or somatic diseases; (5) Patients in the acute phase of cerebrovascular diseases; (6) Patients with adverse reactions to electrical stimulation; (7) Patients with pain sensitivity, injury, or inflammation in the stimulation area.
- Exclusion criteria for MRI;
- Patients with severe neurological, cardiac, liver, kidney, endocrine, and blood system diseases, or any other condition that may interfere with the study evaluation;
- Patients with organic mental disorders and mental retardation;
- Patients with alcohol or drug dependence;
- Patients with a high risk of suicide.
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06061653
Start Date
October 1 2023
End Date
December 31 2025
Last Update
October 31 2023
Active Locations (1)
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1
The First Affiliated Hospital of Zhejiang University
Hangzhou, Zhejiang, China, 310009