Status:
RECRUITING
Cryopreservation of Prepubertal Testicular Tissue for Preservation of Fertility in Young Boys With Cancer
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
University of Oxford
Conditions:
Fertility Disorders
Childhood Cancer
Eligibility:
MALE
1-18 years
Phase:
NA
Brief Summary
Prepubertal boys treated for cancer are at risk of infertility as a result of their treatment. At present there are no options to preserve fertility in these boys. With informed consent, the investiga...
Detailed Description
Objectives 1. Primary Objective a) Cryopreservation of testicular tissue from pre- and peri-pubertal patients undergoing potentially sterilising therapy for future therapeutic use to preserve fer...
Eligibility Criteria
Inclusion
- Pre- and peripubertal boys
- Due to receive cancer treatment that is predicted to have a high risk (\>80%) of infertility
- Consent to removal of testicular tissue for storage and research
- Unable to produce a semen sample by masturbation
Exclusion
- Participation in study would delay treatment
- Too unwell to undergo the procedure
- Pre-existing testicular pathology/previous testicular surgery (eg orchidopexy)
- Able to produce a semen sample for cryopreservation
Key Trial Info
Start Date :
April 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2061
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06063551
Start Date
April 1 2016
End Date
April 1 2061
Last Update
November 20 2025
Active Locations (1)
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1
University of Edinburgh
Edinburgh, Lothian, United Kingdom, EH164TJ