Status:

UNKNOWN

Transcriptional and Proteomic Analysis of Acute Kidney Injury

Lead Sponsor:

University Hospital Muenster

Conditions:

Acute Kidney Injury

Eligibility:

All Genders

18-150 years

Brief Summary

Acute kidney injury is associated with worsened outcome for critically ill patients. Sepsis-associated and non-septic cardiothoracic surgery associated AKI have been reported, nonetheless, precise pat...

Detailed Description

Acute kidney injury is a common and detrimental finding in critically ill/sepsis patients as well as non-septic patients post cardiothoracic surgery. In many cases renal replacement therapy is require...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • study consent;
  • KDIGO\>=2;
  • vasoplegia and/or sepsis or elective nephrectomy.
  • Exclusion criteria:
  • Age\<18 years;
  • pregnancy/nursing;
  • preexisting CKD with eGFR\<60m/min;
  • dialysis; former ogran transplantation;
  • HIV; hematologic malignancies;
  • immunsuppression;
  • 4h post biopsy non-pausable effective anticoagulation;
  • pre-existing coagulopathy

Exclusion

    Key Trial Info

    Start Date :

    September 29 2023

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2024

    Estimated Enrollment :

    60 Patients enrolled

    Trial Details

    Trial ID

    NCT06064305

    Start Date

    September 29 2023

    End Date

    December 1 2024

    Last Update

    October 3 2023

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