Status:
RECRUITING
Potential Diagnostic Biomarkers for Aortic Dissection in the Emergency Department
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Aortic Dissection
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this observational study is to determine the utility of desmosine, D-dimer and aggrecan as early diagnostic biomarkers in aortic dissection. The main questions it aims to answer are: * To...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Presentation to the ED with first 24 hours of symptoms suggesting AD, including chest pain, upper back pain, syncope of unknown cause, symptoms of any acute perfusion deficit
- Confirmed AD
- the diagnosis of AD adjudicated by an independent expert panel at hospital discharge or death, whichever comes first
- The expert panel will consist of (1) a specialist in Emergency Medicine and (2) a specialist in Cardiology and (3) a specialist in Cardiothoracic Surgery.
Exclusion
- Age \<18 years old
- Pregnancy
- Surgery or stenting performed before recruitment
Key Trial Info
Start Date :
June 18 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
47 Patients enrolled
Trial Details
Trial ID
NCT06065306
Start Date
June 18 2023
End Date
December 31 2025
Last Update
April 16 2024
Active Locations (1)
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1
Prince of Wales Hospital
Shatin, NT, Hong Kong