Status:
UNKNOWN
REcruitment MAneuvers and Mechanical Ventilation Guided by EIT in pARDS
Lead Sponsor:
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Conditions:
ARDS
Pediatric Respiratory Distress Syndrome
Eligibility:
All Genders
1-5 years
Phase:
NA
Brief Summary
There is evidence from randomized controlled trials in adult patients with Acute Respiratory Distress Syndrome (ARDS) suggesting that delivering small tidal volumes with adequate levels of Positive En...
Eligibility Criteria
Inclusion
- Intubated and mechanically ventilated children, ageing 1 months-5 years and meeting the PALICC definition for pediatric Acute Respiratory Distress Syndrome (pARDS)
- Informed Consent signed
Exclusion
- Patients with one or more of the following characteristics:
- Previous barotrauma (pneumothorax, pneumomediastinum or subcutaneous emphysema)
- Signs of intracranial hypertension
- Cyanotic congenital cardiac disease
- Dorso-lumbar pathologies or other bone pathologies associated with restrictive lung disease (such as scoliosis, kyphosis)
- Implantable devices not compatible with EIT (such as pace-makers and implantable cardioverter defibrillator)
- Controindication to positioning the esophageal catheter (surgery, esophageal stenosis)
Key Trial Info
Start Date :
January 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 30 2024
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT06067152
Start Date
January 1 2022
End Date
January 30 2024
Last Update
October 4 2023
Active Locations (1)
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1
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico Milano
Milan, Italy, 20122