Status:
COMPLETED
Probiotic Supplementation IN NAFLD Patients
Lead Sponsor:
Ain Shams University
Conditions:
NAFLD
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
this study aimed to evaluate the effectiveness of Probiotics supplementation (lactobacillus) on NAFLD fibrosis score.
Detailed Description
Non-alcoholic fatty liver disease (NAFLD) is a disease characterized by accumulation of fat (\> 5% of the liver tissue), in the absence of alcohol abuse or other chronic liver diseases. NAFLD can caus...
Eligibility Criteria
Inclusion
- Age between18 and 60
- BMI ≥ 25 kg/m2
- Sonographic findings of NAFLD +/- elevated liver enzymes (not more than 2 folds increase).
Exclusion
- ▪ Any evidence of chronic liver diseases including viral hepatitis (B and C), auto immune hepatitis.
- History of alcohol drinking.
- Chronic medication use (drugs that cause elevated liver enzymes, recent antibiotic use or paracetamol use in the last month)
- Persistent elevation of liver enzymes for 3 months.
- History of DM.
- History of statin therapy for cardiovascular disease (CVD).
- History of recent operation.
- History of gastroenteritis or diarrhea in the last 2 week.
Key Trial Info
Start Date :
September 12 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2023
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06074094
Start Date
September 12 2021
End Date
March 1 2023
Last Update
October 10 2023
Active Locations (1)
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1
Ain Shams University
Cairo, Egypt, 11517