Status:
COMPLETED
Treating Respiratory Emergencies in Children Study
Lead Sponsor:
Oregon Health and Science University
Collaborating Sponsors:
University of Utah
University at Buffalo
Conditions:
Asthma in Children
Eligibility:
All Genders
2-17 years
Phase:
PHASE2
Brief Summary
Over 200,000 children have a 911 Emergency Medical Services (EMS) activation for respiratory distress each year, most of whom have acute wheezing. Early treatment in the prehospital setting could more...
Eligibility Criteria
Inclusion
- Ages 2-17 years; AND
- Transported by EMS through 911 activation; AND
- Prior history of wheeze/asthma, current asthma symptoms (dyspnea or wheeze); AND
- At least 4 of the following:
- Visible use of accessory muscles/retractions
- Inspiratory and expiratory wheezing or silent chest
- Abnormal respiratory rate for age
- For \< 6 years ≥ 46 breaths/min
- For ≥ 6 years ≥ 36 breaths/min
- Agitation, drowsiness, or confusion
- Oxygen saturation \< 93% on room air
Exclusion
- History of albuterol, ipratropium, or dexamethasone allergy
- Known or suspected pregnancy
- Prisoner
- Croup
- Suspected airway foreign body
- Respiratory distress not due to bronchospasm/wheeze
- Parent, legally authorized representative (LAR), subject, and/or family member objects to participation prior to treatment
Key Trial Info
Start Date :
February 19 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 11 2025
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT06074185
Start Date
February 19 2024
End Date
March 11 2025
Last Update
May 6 2025
Active Locations (3)
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1
University at Buffalo
Buffalo, New York, United States, 14261
2
Mecklenburg County EMS
Charlotte, North Carolina, United States, 28208
3
University of Utah
Salt Lake City, Utah, United States, 84112