Status:
UNKNOWN
Intrathecal Dexmedetomidine Versus Intrathecal Morphine Inpatients Undergoing Cardiac Valve Replacement Surgeries
Lead Sponsor:
Assiut University
Conditions:
Cardiac Valve Disease
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Comparison between the effects of intrathecal morphine versus intrathecal dexmedetomidine on analgesia and respiratory function, in open heart surgery.
Detailed Description
Postoperative pulmonary dysfunction is a well-recognized complication of open-heart surgeries. About 25% of patients who don't present with any severe impaired cardiac function reported to have signif...
Eligibility Criteria
Inclusion
- \- Cardiac patient scheduled for elective open heart valve replacement surgery.
Exclusion
- • Patient refusal
- Coagulation disorders
- History of known allergy to the used drugs.
- Combined procedures (e.gif combined with coronary artery bypass or aortic root surgeries).
- If thoracotomy or min-sternotomy is planned for the surgery.
- Re-do and emergency surgeries.
- History of chronic chest diseases (COPD or IPF).
- History of thoracotomy, pneumothorax, pneumomediastinum, phrenic nerve injury (as evident by the presence of paralysis of the ipsilateral hemidiaphragm when examined preoperatively).
- Neuromuscular diseases.
- Brain injuries.
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06076759
Start Date
October 1 2023
End Date
November 1 2024
Last Update
October 11 2023
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