Status:
NOT_YET_RECRUITING
Cognitive Remediation of Working Memory Post Head Trauma
Lead Sponsor:
University Hospital, Toulouse
Conditions:
Head Trauma
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Patients with working memory deficits due to a moderate to severe head injury will undergo a 5 month protocol including cognitive remediation with numerous exercises, transcranial direct current stimu...
Detailed Description
This study is a multiple baseline Single Case Experimental Design (SCED) across 3 patients and 2 behaviors (working memory performance, application of compensatory strategies). The remediation progra...
Eligibility Criteria
Inclusion
- Moderate or severe head trauma, defined by an initial Glasgow score ≤ 12/15, duration of post-traumatic amnesia superior to 24 hours and/or the presence of abnormalities on brain imaging,
- Moderate or severe head trauma occurring within a period greater than or equal to 3 months,
- Working memory complaints assessed by the Working Memory Questionnaire,
- Patients with a working memory disorder in at least one of the following tests: Digit Memory subtest WAIS-IV (standard deviation ≤ -2) , PASAT (percentile ≤ 10), Brown-Peterson (standard deviation ≤ -2).
Exclusion
- Presence of aphasia, apraxia or severe neglect demonstrated by standardized neuropsychological tests during the inclusion visit: language - oral naming of BECS-GRECO images, ideational praxis and ideomotor , neglect - bell test,
- Insufficient visual or auditory abilities and oral and written expression to carry out neuropsychological tests,
- Severe depression assessed by the Beck Depression Inventory (BDI)
- Chronic alcoholic poisoning, drug addiction,
- Progressive general illness,
- Progressive psychiatric or neurological condition leading to cognitive impairment,
- Hospitalization for a neurological pathology since the acute phase of the qualifying event,
- Patient requiring surgery during study participation.
- Pregnant or breastfeeding women
Key Trial Info
Start Date :
December 30 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT06077695
Start Date
December 30 2024
End Date
December 30 2025
Last Update
June 17 2024
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.