Status:

UNKNOWN

Phase 1 Clinical Study of JMKX003142 Tablets

Lead Sponsor:

Jemincare

Collaborating Sponsors:

Zhejiang Hangyu Pharmaceutical Co., Ltd.

Conditions:

Safety and Tolerability

Eligibility:

All Genders

18-45 years

Phase:

PHASE1

Brief Summary

Phase I clinical study to evaluate the safety, tolerability, and pharmacokinetic characteristics of JMKX003142 tablets administered randomly, double-blind, placebo-controlled single and multiple times...

Eligibility Criteria

Inclusion

  • Male and female subjects aged 18-45 years (including boundary values)
  • Able to sign a written informed consent form
  • Physical examination, clinical laboratory examination value, Virology examination, vital signs and 12 lead ECG examination are confirmed by the researcher to be normal or abnormal without clinical significance
  • The subjects have a thorough understanding of the study content, process, and potential adverse effects, and are willing to complete the study according to the requirements of the experimental protocol

Exclusion

  • Had or currently have serious clinical diseases related to circulatory system, respiratory system, digestive system, nervous system, endocrine system, blood lymphatic system, genitourinary system or psychiatry, as well as habitual constipation, gastrointestinal bleeding history, which is judged to be inappropriate for the study by the investigators
  • Participants in any other clinical study within 3 months prior to the first administration of this study
  • The investigators believe that the subject has other factors that are not suitable for participating in this experiment
  • Pregnant or lactating women

Key Trial Info

Start Date :

July 6 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 30 2025

Estimated Enrollment :

106 Patients enrolled

Trial Details

Trial ID

NCT06079541

Start Date

July 6 2023

End Date

March 30 2025

Last Update

October 17 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Zhongshan Hospital, Fudan University

Shanghai, Shanghai Municipality, China