Status:
RECRUITING
Personality and Quality of Life Amelioration After Continuous Subcutaneous Apomorphine Infusion in Parkinson's Disease
Lead Sponsor:
University Hospital, Toulouse
Collaborating Sponsors:
ELIVIE France
EVER Pharma France SAS
Conditions:
Parkinson Disease
Eligibility:
All Genders
18+ years
Brief Summary
Since our previous study has shown that some personality dimensions were associated with Quality of Life (QoL) amelioration after Deep Brain Stimulation (DBS) in Parkinson's disease (PD), the investig...
Detailed Description
As Parkinson's disease (PD) progresses, the onset of motor and non-motor fluctuations alters patients Quality of Life (QoL). Second-line treatments can then be proposed: either the implantation of dee...
Eligibility Criteria
Inclusion
- Parkinson's disease patients as defined by the United Kingdom Parkinson's disease Brain Bank (UKPDSBB) criteria and aged from 40 to 75 years old (included)
- Patients with motor fluctuations and/or invalidating dyskinesia and awaiting CSAI establishment in the context of their usual care for PD
- Patients affiliated to a social security system
Exclusion
- Patients presenting an atypical parkinsonian syndrome Patients having a Deep Brain Stimulation
- Patients with a psychiatric disease such as bipolar disorder or delusions linked to a dopaminergic psychosis
- Patients presenting a cognitive deficit attested by a score to the Montreal Cognitive Assessment inferior to 24, solely during the inclusion (baseline - V0)
- Patient with a serious pathology (e.g. cancer) or a health condition which could interfere with the assessment of their quality of life, at the discretion of the investigator upon inclusion
- Patients under guardianship, curatorship or safeguard of justice
- Patients under exclusion period from another study
Key Trial Info
Start Date :
February 15 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2026
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT06080399
Start Date
February 15 2024
End Date
April 1 2026
Last Update
August 29 2024
Active Locations (10)
Enter a location and click search to find clinical trials sorted by distance.
1
Chu de Lyon
Bron, France
2
Hopital Gabriel Montpied
Clermont-Ferrand, France
3
Chu de Grenoble
Grenoble, France
4
Chu Limoges
Limoges, France