Status:

RECRUITING

Contribution of PET/MRI in Locally Advanced Cervical Cancer (ATICC)

Lead Sponsor:

Institut de cancérologie Strasbourg Europe

Conditions:

Cervical Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

\[18 F\]fluorodeoxyglucose (18F-FDG) positron emission tomography-magnetic resonance imaging (PET/MRI) is a new hybrid imaging tool that has recently arrived in oncology, and is particularly promising...

Detailed Description

This monocentric, prospective trial aims at comparing performances of 18F-FDG PET/MRI versus standard PET/CT in the detection of lymph node metastases in cervical cancer patients. Specificity and sens...

Eligibility Criteria

Inclusion

  • Patients aged from 18 years old and over
  • Patients with presumed cervical cancer of stages IB2 to IVA based on clinical data and pelvic MRI, undergoing pre-treatment assessment.
  • For women of childbearing potential : Adequate contraception throughout study participation.
  • Note : enrollment in a concomitant clinical trial is authorized

Exclusion

  • Oncological history that could possibly interfere with imaging results interpretation, apart from cervical cancer
  • Extra-nodal metastasis clinically or radiologically proven before study participation
  • Contraindication to MRI or injection of contrast agents containing gadolinium
  • Contraindication to lumbo-aortic lymphadenectomy
  • Persons deprived of liberty
  • Minor or patients placed under guardianship or supervision
  • Patient under judicial protection
  • Patient unable to consent

Key Trial Info

Start Date :

October 12 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06083103

Start Date

October 12 2023

End Date

December 31 2025

Last Update

March 13 2024

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Institut de cancérologie Strasbourg Europe

Strasbourg, France, 67033