Status:

COMPLETED

Long Term Effects of Heat and Moisture Exchangers (HMEs)

Lead Sponsor:

Atos Medical AB

Collaborating Sponsors:

Instituto de Cancer Dr Arnaldo

Conditions:

Laryngectomy; Status

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Assessment of long term effect of Provox Life HME use on pulmonary symptoms in laryngectomized patients.

Eligibility Criteria

Inclusion

  • Total laryngectomy, irrespective of pharynx reconstruction method
  • 18 years or older
  • Longer than 3 months after total laryngectomy
  • Longer than 6 weeks after postoperative radiotherapy

Exclusion

  • Current use of HMEs (within last 3 months)
  • Medical problems prohibiting the use of HME
  • Active recurrent or metastatic disease (medical deterioration)
  • Recent pulmonary infections/unstable pulmonary condition
  • Insufficient physical, cognitive, or mental ability required to attach, remove or operate the devices themselves
  • Low tidal volumes
  • Unable to understand the Participant Information and/or unable to give Informed Consent

Key Trial Info

Start Date :

March 26 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 30 2025

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06084611

Start Date

March 26 2024

End Date

September 30 2025

Last Update

October 3 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Instituto de Cancer Dr. Arnaldo

São Paulo, Brazil