Status:
RECRUITING
Effect of Structured Exercise in Patients With Knee Osteoarthritis
Lead Sponsor:
The Hong Kong Polytechnic University
Collaborating Sponsors:
Kwong Wah Hospital
Conditions:
Osteoarthritis, Knee
Physical Inactivity
Eligibility:
All Genders
55+ years
Phase:
NA
Brief Summary
The aim of this randomized controlled trial is to evaluate the effect of Nordic walking and inspiratory muscle training (IMT) on cardiopulmonary function in patients with knee osteoarthritis (OA). Mil...
Detailed Description
This study recruits patients with different stages and assigns them into different interventions and comparing the effect with those not receiving intervention. It will provide the evidence in terms o...
Eligibility Criteria
Inclusion
- pain on the most days in one or both knees in the past month;
- difficulty with at least one of daily living activities measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale;
- radiographic evidence of knee OA in the tibial-femoral compartment (Kellgren and Lawrence grade, K/L ≥1, K/L 1-3 regarded as mild-to-moderate knee OA, others waiting for knee arthroplasty regarded as end-stage knee OA);
- with normal or corrected visual and auditory function and walking unaided;
- primary knee OA for more than 6 months, be stable on medication for at least 3 weeks.
Exclusion
- knee surgery priorly;
- have steroid injection in previous three weeks;
- have inflammatory arthritis (e.g., rheumatoid); or unstable angina, or myocardial infarction, or cardiac surgery; or stroke; or treatment with steroids, hormones, or cancer chemotherapy; or pulmonary diseases (force vital capacity\<80% of predicted and/or forced expiratory volume at first second\<70% of predicted); or a history of exercise-induced asthma;
- unable to understand the procedure and potential risks of the study;
- medically unstable that indicate unsafe to participate in exercise test
Key Trial Info
Start Date :
October 5 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06084949
Start Date
October 5 2023
End Date
August 31 2026
Last Update
October 16 2023
Active Locations (1)
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1
The Hong Kong Polytechnic University
Kowloon City, Kowloon, Hong Kong