Status:
ACTIVE_NOT_RECRUITING
Investigating Age-dependent Effects of Egg Intake on HDL and Immune Profiles
Lead Sponsor:
University of Connecticut
Collaborating Sponsors:
American Egg Board
Conditions:
Lipoproteins
Inflammatory Response
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The goal of this intervention study is to determine whether consumption of different fractions of chicken eggs, including egg whites, egg yolks, and whole eggs, confer different changes in markers of ...
Eligibility Criteria
Inclusion
- 18-30 years old, or 50-75 years old (at time of screening)
- Body mass index (BMI) \< 30 kg/m2
- Willing to consume whole eggs, egg whites, or egg yolks on a daily basis during study periods, and refrain from eating eggs during other study periods
- Do not fit any exclusion criteria
Exclusion
- \< 18 years old; 31-49 years old; \> 75 years old
- BMI ≥ 30 kg/m2 or body weight \< 110 pounds
- Weight changes \> 10% over the last 4 weeks
- Self-reported history of diabetes, heart disease, stroke, renal or liver disease, cancer, eating disorders, certain severe and/or relapsing/remitting autoimmune, inflammatory, or metabolic diseases, chronic infections, scleroderma, blood clotting disorders, intravenous drug use, or current pregnancy or lactation
- Allergy or intolerance to eggs, egg components, or egg products
- Implanted medical device (e.g., pacemaker) or other health condition that would prevent measurement of body composition by bioelectrical impedance
- Highly elevated fasting lipid and glucose levels (triglyceride levels higher than 500 mg/dL, fasting glucose higher than 126 mg/dL), or total cholesterol \< 120 mg/dL and HDL-cholesterol \< 15 mg/dL
- Currently taking lipid-lowering medications (e.g. statins, fibrates), anti-inflammatory medications (e.g., NSAIDs, corticosteroids), or medications that primarily affect blood clotting (e.g., warfarin)
Key Trial Info
Start Date :
January 23 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT06086795
Start Date
January 23 2024
End Date
June 1 2026
Last Update
August 5 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Connecticut
Storrs, Connecticut, United States, 06269