Status:
COMPLETED
Low vs. Air Oxygen Concentration CAPA-IVM Culture of Cumulus-oocyte Complexes
Lead Sponsor:
Mỹ Đức Hospital
Conditions:
IVM
PCOS (Polycystic Ovary Syndrome)
Eligibility:
FEMALE
18-37 years
Phase:
NA
Brief Summary
IVM with a pre-maturation step, known as capacitation IVM (CAPA-IVM), has demonstrated enhanced maturation of human oocytes in vitro and successful live births. However, CAPA-IVM has shown lower rates...
Detailed Description
Oocyte in vitro maturation (IVM) is an alternative approach to assisted reproductive technology (ART) that has the advantage of minimal stimulation, resulting in reduced hormone-related side effects a...
Eligibility Criteria
Inclusion
- ≤38 years
- Having polycystic ovarian morphology: at least 25 follicles (2-9 mm) throughout the whole ovary and/or increased ovarian volume (\>10ml)
- Having at least 20 follicles on the Oocyte Pick-up day
- Patients consent to culture embryos to the blastocyst
Exclusion
- Cases with severe male factor (concentration \<5 million/ml, cryptozoospermia, azoospermia)
- Oocyte donation
- Pre-implantation genetic testing
Key Trial Info
Start Date :
November 9 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 22 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06087354
Start Date
November 9 2023
End Date
May 22 2024
Last Update
June 3 2024
Active Locations (1)
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1
My Duc Hospital
Ho Chi Minh City, Vietnam, 70000