Status:
RECRUITING
Speech-in-noise Perception in Autism and Fragile X
Lead Sponsor:
Children's Hospital Medical Center, Cincinnati
Conditions:
Autism Spectrum Disorder
Fragile X Syndrome
Eligibility:
All Genders
15-35 years
Phase:
NA
Brief Summary
The goal of this study is to identify which brain regions are active during speech-in-noise perception, as well as how those regions interact. The investigators are studying brain activation during sp...
Detailed Description
Participants will be 15-35 year-olds with autism, Fragile X Syndrome and autism, and a typical developing group, matched on age and sex (n=20 per group). These ages are wide enough to support sufficie...
Eligibility Criteria
Inclusion
- normal audiograms (PTA ≤ 20 dB HL)
- corrected 20/20 vision (Snellen chart)
- no history of premature birth (prior to 36 weeks gestation)
- no medications known to affect EEG signal
- English as the first language
- Inclusion for the Autism group requires the following:
- 1\) diagnosis of Autism Spectrum Disorder either based on previous ADOS administration and developmental history, or confirmed via ADOS and developmental history
- Inclusion for the Autism + FXS group requires the following:
- Documented PCR/Southern Blot genetic testing confirming full mutation FXS
- Diagnosis of Autism Spectrum Disorder, per Autism group.
- Inclusion for the Typically Developing group requires the following:
- no siblings or parents with an Autism Spectrum Disorder or Fragile X Syndrome
- no current neurological or psychiatric diagnoses
- IQ over 75
Exclusion
- Hearing loss or uncorrected vision loss
- history of premature birth (prior to 36 weeks gestation)
Key Trial Info
Start Date :
November 10 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06088589
Start Date
November 10 2023
End Date
April 30 2025
Last Update
February 18 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cincinnati Children'S Hospital
Cincinnati, Ohio, United States, 45229-3026