Status:
NOT_YET_RECRUITING
Pro-social Power Training Activity for Aging and Well-being With Chronic Kidney Disease
Lead Sponsor:
VA Office of Research and Development
Conditions:
Lower Extremity Muscle Strength
Eligibility:
All Genders
Phase:
NA
Brief Summary
This is a pilot trial of a 16-week physical activity and power training program among 30 Veterans/arm with advanced chronic kidney disease. The trial aims to test whether the program is tolerable to V...
Detailed Description
This will be a randomized controlled pilot trial of a 16-week physical activity and power training intervention trial among 30 pre-frail Veterans with Stage 3B-5 chronic kidney disease. The interventi...
Eligibility Criteria
Inclusion
- Participant's nephrologist and/or primary care physician agree that participant may enroll in trial
- Participants classified as pre-frail per Fried Frailty phenotype due to slowness (time taken to walk 15 feet is greater than 6 seconds) in Aim 1, OR who report 'YES' to any of the following:
- "For health or physical reasons, do you have difficulty in walking a mile (5-6 blocks)?", OR
- "If no, have you changed the way you walk half a mile (5-6 blocks) because of underlying health problems?", OR
- "For health or physical reasons, do you have difficulty in climbing 1 flight of stairs (10 steps)?", OR
- "If no, have you changed the way you climb 1 flight of stairs (10 steps) because of health problems?"
Exclusion
- Myocardial infarction or unstable angina within the prior six months based on electronic medical record review or self-report
- Uncontrolled cardiac arrythmia within the prior six months based on electronic medical record review or self-report
- Systolic blood pressure \> 180 mm Hg and/or diastolic blood pressure \> 110 mm Hg on more than one occasion within prior six months based on electronic medical record review or self-report
- Cerebrovascular event and/or transient ischemic attack within prior six months based on electronic medical record review or self-report
- Abnormal cardiac stress test within the past year based on electronic medical record review or self-report
- Hemoglobin of 10 g/dL or less based on electronic medical record review or self-report
- Class IV heart failure based on electronic medical record review or self-report
- Dyspnea and/or chest pain at rest
- Dependence on wheelchair for mobility
- Permanent residence in nursing home or other long-term care facility
- Terminal illness or other hospice-qualifying medical condition
- Planned move away from middle Tennessee within the next year
- Planned major surgery in the next six months
- Blindness
- Concurrent enrollment in physical therapy or structured exercise program
- Anticipated dialysis or kidney transplant in upcoming three months
- Non-English speaking
- Severe cognitive impairment based on electronic medical record review or self-report
Key Trial Info
Start Date :
March 2 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2029
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06089057
Start Date
March 2 2026
End Date
April 1 2029
Last Update
July 17 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Tennessee Valley Healthcare System Nashville Campus, Nashville, TN
Nashville, Tennessee, United States, 37212-2637