Status:
COMPLETED
Characteristics of Renal Blood Flow in AKI Patients in ICU and Its Clinical Significance
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Acute Kidney Injury
Renal Artery Blood Flow
Eligibility:
All Genders
18-85 years
Brief Summary
To study the changes in the renal artery and renal vein with renal cortical and medullary microcirculatory blood flow in patients with sepsis; to study the relationship between renal arteriolar and re...
Eligibility Criteria
Inclusion
- Age between 18-85 years old; Control group: patients with non-acute kidney injury after ICU general surgery; Observation group: patients who met the diagnostic criteria of AKI: Scr elevation ≥26.5 umol/L within 48h; Scr elevation exceeding 1.5 times and more than the basal value within 7d; and decrease in urine output (\<0.5 ml/kg/h) with a duration of 6h or more.
Exclusion
- Those who did not meet the inclusion criteria or refused to be enrolled; patients with underlying end-stage renal disease or requiring long-term dialysis; renal transplant patients; patients with other underlying systemic diseases causing renal dysfunction (SCr \> 88.4 umol/L); those who were unable to obtain a clear renal ultrasound view; those with suspected contrast allergy; those with pulmonary arterial systolic blood pressure ≥ 90 mm Hg; and those who were pregnant or breastfeeding women.
Key Trial Info
Start Date :
June 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 30 2023
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT06090773
Start Date
June 1 2023
End Date
December 30 2023
Last Update
February 9 2024
Active Locations (1)
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1
Rongping Chen
Beijing, Beijing Municipality, China, 100730