Status:
UNKNOWN
Analysis of Urinary, Vaginal and Intestinal Microbiota in Patients With Neurogenic Bladder
Lead Sponsor:
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions:
Microbial Colonization
Eligibility:
FEMALE
18-50 years
Brief Summary
The neurogenic bladder and bowel are two pathological conditions occurring when damaged innervation results in functional alteration of both the bladder and the bowel with a clinical presentation that...
Eligibility Criteria
Inclusion
- For both populations:
- childbearing age
- no antibiotic therapies in the last 30 days
- no urinary tract infections/diseases in the last 30 days
- no surgical interventions in the last 90 days
- no intake of prebiotics or probiotics in the last 60 days
- no estrogen-progestin or steroid hormone therapy in the last 60 days
- no sexual intercourse in the last 3 days
- no local vaginal therapy in the last 60 days
- signing of the informed consent;
- patients without lower urinary tract disorders (only for the control group);
- patients with neurogenic bladder secondary to spina bifida (only for the study group).
Exclusion
- For both populations:
- kidney or urinary tract stones
- presence of pre-existing or ongoing intestinal pathologies (Inflammatory Bowel Diseases, chronic hepatitis, celiac disease, neoplasms, previous extensive intestinal resections)
- ongoing diarrhea of any origin (defined as more than 6 evacuations of watery stools per day and/or faecal volume in 24 hours greater than 250 ml)
- ongoing septic status
- state of pregnancy
Key Trial Info
Start Date :
November 10 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06093035
Start Date
November 10 2023
End Date
December 31 2024
Last Update
October 23 2023
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