Status:

UNKNOWN

Immune Markers in Pediatric ITP on Second Line Therapy

Lead Sponsor:

Assiut University

Conditions:

ITP - Immune Thrombocytopenia

Eligibility:

All Genders

Up to 17 years

Brief Summary

Immune thrombocytopenia (ITP) is a common autoimmune disease characterized by low platelet count and increased risk of bleeding. It affects approximately 50 to 100 cases per million people per year, w...

Detailed Description

Antiplatelet factors in the plasma of ITP patients, specifically IgG, have been attributed to platelet destruction through phagocytosis or complement-mediated lysis. However, these antibodies are only...

Eligibility Criteria

Inclusion

  • Pediatric patients diagnosed with immune thrombocytopenia who are undergoing second line therapy with either eltrombopag or romiplostim.

Exclusion

  • Include acute immune thrombocytopenic children receiving first line therapy and those with secondary immune thrombocytopenia.

Key Trial Info

Start Date :

January 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2025

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT06093529

Start Date

January 1 2024

End Date

February 1 2025

Last Update

November 14 2023

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