Status:
RECRUITING
Hypotensive Anesthesia for Orthognathic Surgery
Lead Sponsor:
Boston Medical Center
Conditions:
Hypotensive Anesthesia
Orthognathic Surgery
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The overall objective of this double blinded, randomized controlled trial (RCT) is to compare specific outcomes of three medications (Dexmedetomidine, Nicardipine, and Labetalol) which are routinely u...
Eligibility Criteria
Inclusion
- Adult patients undergoing orthognathic surgery \[Le Fort I, Surgically Assisted Rapid Palatal Expansion (SARPE), Bilateral Sagittal Split Osteotomy (BSSO), or a combination these surgeries\] at Boston Medical Center with Dr. Mehra
- Healthy, American Society of Anesthesiologists (ASA) physical status classification system I or II
Exclusion
- Patients on a home beta blocker
- Patients on home calcium channel blocker
- Patients on home alpha 2 agonists
- Patients with an allergy to one or more of the intervention medications
- Does not speak English
- Pregnant patients (this is assessed day of surgery per standard care with a urine pregnancy test)
- Patients who have contraindications to induced hypotensive anesthesia
Key Trial Info
Start Date :
March 4 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06093893
Start Date
March 4 2025
End Date
March 1 2026
Last Update
December 30 2025
Active Locations (1)
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1
Boston Medical Center
Boston, Massachusetts, United States, 02118