Status:

COMPLETED

Tobacco and Alcohol Influence on Oncogenic Drivers and Somatic Evolution in the Oral Mucosa

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Carcinoma, Squamous Cell

Eligibility:

All Genders

18+ years

Brief Summary

Head and neck cancers represent more than 500,000 cases per year worldwide, and often involve post-treatment relapse. The oral cavity is the most frequent site, but early disease stages are still insu...

Eligibility Criteria

Inclusion

  • Man or woman aged 18 or more.
  • Subject coming to odontology practice for routine visit.
  • Subject having accepted to participate to the research by oral non-opposition
  • Subject having given additional written consent for genetic studies.
  • Smoking group criterion: subjects having smoked 100+ cigarettes/joints during their life.

Exclusion

  • Personal history of cancer, whichever the type.
  • Treatment with anticoagulants or platelet aggregation inhibitors.
  • Bilateral lesions of the inner cheek preventing painless biological sample collection.
  • Subject under under guardians or curators
  • Pregnancy or breastfeeding
  • Cannabis usage

Key Trial Info

Start Date :

November 23 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 8 2024

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06094829

Start Date

November 23 2023

End Date

March 8 2024

Last Update

June 26 2024

Active Locations (15)

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Page 1 of 4 (15 locations)

1

Cabinet Libéral Picquendar

Bougival, France, 78380

2

Cabinet Libéral Balayre

Chassieu, France, 69680

3

Cabinet Libéral Debeauvais

Châtillon-Coligny, France, 45230

4

Cabinet Libéral Finet

Fontaine-lès-Dijon, France, 21121