Status:
UNKNOWN
The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin
Lead Sponsor:
Integrative Skin Science and Research
Collaborating Sponsors:
Sytheon Ltd.
Conditions:
Photoaging
Eligibility:
FEMALE
40-60 years
Phase:
NA
Brief Summary
This study is a double-blind randomized vehicle-controlled study assessing how Zinc Di-(dibutyryl lisinate) (Z-DBL) influences skin biophysical measures such as skin hydration, transepidermal water lo...
Eligibility Criteria
Inclusion
- Females between the ages of 40 years of age until 60 years of age
- Participants must have facial fine lines and wrinkles
- Subjects must minimize sun exposure
- Subjects must avoid professional or facial spa procedures during the study
Exclusion
- Individuals who are pregnant or breastfeeding.
- Prisoners.
- Adults unable to consent.
- Those who are unwilling to discontinue topical hydroquinone, retinoids, bakuchiol, vitamin C, or acetyl zingerone containing products for two weeks to meet the washout criteria prior to enrolling.
- Those who are unwilling to discontinue topical antibiotics and benzoyl peroxide for two weeks to meet the washout criteria prior to enrolling.
- Those who have been on an oral antibiotic within 1 month prior to enrolling.
- Subjects with any of the following facial cosmetic treatments in the past 3 months or those who are unwilling to withhold the following facial cosmetic treatments during the study including botulinum toxin, injectable fillers, microdermabrasion, intense pulsed light (IPL), peels, laser treatments, acid treatments, facial plastic surgery, or any other medical treatment administered by a physician or skin care professional which is designed to improve the appearance of facial skin.
- Those who are unwilling to discontinue all facial topical products except the product provided in the study.
- Individuals who have changed any of their hormonal based contraception within 3. months prior to joining the study.
- Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years.
Key Trial Info
Start Date :
October 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2024
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT06096649
Start Date
October 15 2023
End Date
September 1 2024
Last Update
October 24 2023
Active Locations (1)
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1
Integrative Skin Science and Research
Sacramento, California, United States, 95819