Status:

COMPLETED

Fetuin-A, a Promising Serum Biomarker for Diagnosis of Non-Alcoholic Fatty Liver Disease

Lead Sponsor:

Zagazig University

Collaborating Sponsors:

Suez University

Benha University

Conditions:

Non-Alcoholic Fatty Liver Disease

Eligibility:

All Genders

18+ years

Brief Summary

The work investigate the role of fetuin-A in the diagnosis and assessment of the severity of non-alcoholic fatty liver disease (NAFLD).

Detailed Description

The prevalence of nonalcoholic fatty liver disease (NAFLD), which has recently become one of the most prevalent chronic liver illnesses, is about 25% worldwide. NAFLD is a progressive liver disease th...

Eligibility Criteria

Inclusion

  • patients who were admitted to the university hospitals with inclusion criteria

Exclusion

  • Patients who are younger than 18 years old,
  • Patients with a history of high alcohol consumption (more than 40 g/day for men and 20 g/day for women) over the previous five years,
  • Patients who have concurrent hepatitis B and hepatitis C viral infections
  • Patients with hepatobiliary malignancy, Wilson's disease, alpha-one antitrypsin deficiency, and autoimmune hepatitis,
  • Pregnant women
  • Patients who take steatogenic pharmaceuticals including amiodarone, valproic acid, antiretrovirals, methotrexate, and tetracyclines, or NAFLD treatments like vitamin E, metformin, and thiazolidinediones

Key Trial Info

Start Date :

January 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 20 2024

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06097039

Start Date

January 1 2023

End Date

February 20 2024

Last Update

July 24 2024

Active Locations (1)

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Zagazig University

Zagazig, Sharqia Province, Egypt, 44511