Status:
UNKNOWN
Intermittent Exogenous Ketosis (IEK) at High Altitude
Lead Sponsor:
Jozef Stefan Institute
Collaborating Sponsors:
KU Leuven
University of Lausanne
Conditions:
Ketosis
Hypoxia
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
Altitude-related hypoxia decreases human functional capacity, especially during exercise. Even with prolonged acclimatization, the physiological adaptations are insufficient to preserve exercise capac...
Eligibility Criteria
Inclusion
- Males or females between 18 and 35 years old
- Body Mass Index (BMI) between 18 and 25
- Physically fit and regularly involved in physical activity (2-5 exercise sessions of \> 30min per week)
- Good health status confirmed by a medical screening
- Non smoking
Exclusion
- Any kind of injury/pathology that is a contra-indication for hypoxic exposure and/or to perform high-intensity exercise
- Intake of any medication or nutritional supplement that is known to affect exercise, performance or sleep
- Intake of analgesics, anti-inflammatory agents, or supplementary antioxidants, from 2 weeks prior to the start of the study.
- Recent residence or training under hypoxia; more than 7 days exposure to altitude \> 2000m during a period of 3 months preceding the study.
- Night-shifts or travel across time zones in the month preceding the study
- Blood donation within 3 months prior to the start of the study
- Smoking
- More than 3 alcoholic beverages per day
- Involvement in elite athletic training at a semi-professional or professional level
- Any other argument to believe that the subject is unlikely to successfully complete the full study protocol
Key Trial Info
Start Date :
September 18 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2024
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT06097754
Start Date
September 18 2023
End Date
June 30 2024
Last Update
October 24 2023
Active Locations (2)
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1
KU Leuven
Leuven, Belgium, 3001
2
Jozef Stefan Institute
Ljubljana, Slovenia, 1000