Status:
RECRUITING
Wrist Denervation Vs Exercise in Wrist Osteoarthritis
Lead Sponsor:
Karolinska Institutet
Conditions:
Osteoarthritis Wrist
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis.
Detailed Description
Backgroud: High quality evidence regarding the effectiveness of non-operative and operative treatments in wrist osteoarthritis are lacking. Aim: To analyze: 1. Does partial wrist denervation and s...
Eligibility Criteria
Inclusion
- Age ≥ 18 years.
- Chronic wrist pain (≥6 months) due to Scapholunate advanced collapse (SLAC) / Scaphoid non-union advanced collapse (SNAC) grade 1-3 osteoarthritis.
- Radiological signs of osteoarthritis on posteroanterior and lateral radiograph.
Exclusion
- Previous PIN or AIN neurectomy.
- Rheumatoid arthritis or other chronic inflammatory arthritis.
- Symptomatic osteoarthritis in the distal radio-ulnar (DRU), Scapho-trapezio-trapezoid (STT) or thumb carpometacarpal (CMC) joints.
- Ongoing infection.
- Inability to co-operate with the follow-up protocol.
- Systemic or intra-articular glucocorticoids or intraarticular PRP or Hyaluronic acid injections in the affected joint within 3 months prior to enrollment.
Key Trial Info
Start Date :
November 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 15 2027
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT06098586
Start Date
November 15 2023
End Date
November 15 2027
Last Update
February 21 2025
Active Locations (2)
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1
Department of hand surgery, Malmo university hospital
Malmo, Sweden, 20502
2
Department of hand handsurgery, Södersjukhuset
Stockholm, Sweden, 11883