Status:

NOT_YET_RECRUITING

Combination Chemotherapy of Paclitaxel and Carboplatin With or Without Anthracycline as Aneo Adjuvant Treatment in Advanced Endometrial Carcinoma

Lead Sponsor:

Sohag University

Conditions:

Endometrial Carcinoma

Eligibility:

FEMALE

20-70 years

Phase:

NA

Brief Summary

Endometrial cancer, the most common gynecologic cancer worldwide, is steadily increasing in developed countries.The early-stage forms of endometrial cancer are usually highly curable by surgical treat...

Eligibility Criteria

Inclusion

  • • Age group: Histologically diagnosed with primary endometrial carcinoma
  • more than 20 years old.
  • Any histological type of endometrial carcinoma
  • Stage III, IV
  • Stage one I or II with one or more of the following factors:
  • Histologic grade 3 endometroid carcinoma with myometrial invasion still within half of the myometrium
  • histological grade 1,2 endometroid carcinomas with invasion of over half of myometrium
  • cervical stromal invasion
  • vascular invasion; or
  • serous carcinoma, clear cell carcinoma, or undifferentiated carcinoma
  • performance status 0-2
  • adequate function of all major organs

Exclusion

  • • Pt has received prior radiation or chemotherapy.
  • Pt with sarcomatous component
  • Metastatic endometrial carcinoma
  • Other malignancy
  • Unfit patient for chemotherapy

Key Trial Info

Start Date :

August 15 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2025

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06102252

Start Date

August 15 2024

End Date

August 1 2025

Last Update

August 6 2024

Active Locations (1)

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Sohag university Hospital

Sohag, Egypt, Sohag