Status:

COMPLETED

Qualitative Techniques to Define Meaningful Within-Patient Change in Symptoms of Advanced Cancer Patients

Lead Sponsor:

Mayo Clinic

Conditions:

Hematopoietic and Lymphoid System Neoplasm

Malignant Solid Neoplasm

Eligibility:

All Genders

18+ years

Brief Summary

This study examines qualitative techniques in defining meaningful within patients changes in symptoms in patients with cancer that may have spread from where it first started to nearby tissue, lymph n...

Detailed Description

PRIMARY OBJECTIVES: I. To develop method to establish meaningful change in patient-reported outcomes (PROs). II. To provide responder definitions in 2 ways: IIa: Detectable change: within patient s...

Eligibility Criteria

Inclusion

  • PATIENTS
  • Patients with a diagnosis of cancer including solid tumor and hematologic malignancy at Mayo Clinic, Rochester
  • To ensure sampling patients likely to have experienced declines in fatigue, all patients will have had at least two in-person encounters for radiation or chemotherapy treatment within the 3 months prior to recruitment. The sampling methodology developed for the Consumer Assessment of Healthcare Providers and Systems (CAHPS) Cancer Care survey will be modified and used to identify eligible patients from Mayo Clinic's electronic health record
  • As interviews will be conducted either in person or by video conference (Zoom, Teams, or similar), access to internet is required for those unable or unwilling to travel to the clinic for an in-person interview
  • Answered "Yes" to screening question: "In the past 3 months, have you experienced changes in your level of fatigue?" Yes/No
  • PATIENT ADVOCATES:
  • Patient advocates recommended by the FDA to provide their input to help us in reaching a consensus in the way we define meaningful change (both improvement and decline) that came from patients in the first arm

Exclusion

  • PATIENTS
  • Unwilling to be audio recorded during the interviews
  • Answered "No" for the screening question

Key Trial Info

Start Date :

May 31 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 7 2023

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06104657

Start Date

May 31 2023

End Date

August 7 2023

Last Update

December 2 2024

Active Locations (1)

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Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905