Status:
WITHDRAWN
A Study in Adults With Advanced Classical Hodgkin's Lymphoma (cHL) in Brazil Treated With Brentuximab Vedotin Together With Chemotherapy Compared to Chemotherapy Alone
Lead Sponsor:
Takeda
Conditions:
Hodgkin Lymphoma
Eligibility:
All Genders
18+ years
Brief Summary
The main aim of this study conducted in Brazil is to understand if there is a difference in the length of time that Classical Hodgkin's Lymphoma (cHL) does not grow or spread further (also called prog...
Detailed Description
This is an observational, multicenter and retrospective study to evaluate the effectiveness of A+AVD regimen compared to ABVD regimen as first-line therapy for the treatment of Brazilian participants ...
Eligibility Criteria
Inclusion
- Histologically confirmed diagnosis of advanced cHL (International Classification of Diseases and Related Health Problems 10th Revision \[ICD-10\] code C81.X). The diagnosis of cHL will be confirmed according to World Health Organization (WHO) classification. Advanced disease is defined as having the diagnosis at stage IIB, III or IV, based on Ann Arbor classification.
- Who received at least one full cycle of A+AVD or ABVD regimen as first-line treatment (first systemic therapy for cHL management; systemic therapy naïve participants) from July, 1st 2017 to December, 31st 2020; and who completed the 6-cycle treatment until the end of December 2020.
- At least 2 years of retrospective information from the index date (treatment window) and at least 2 years of follow-up (after the end of treatment).
Exclusion
- With previous or concurrent malignancies, except participants with completely excised carcinoma in situ of any type and basal or squamous cell carcinoma of the skin.
- Who are simultaneously participating in another study.
- Who participated in the ECHELON-1 Clinical Study.
Key Trial Info
Start Date :
December 31 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 31 2024
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT06104878
Start Date
December 31 2023
End Date
October 31 2024
Last Update
March 6 2024
Active Locations (6)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital São Rafael - Instituto D'Or de Pesquisa e Ensino
Salvador, Estado de Bahia, Brazil, 41253-190
2
Instituto D'Or de Pesquisa e Ensino
Brasília, Federal District, Brazil, 70390-140
3
Oncoclinicas Rio de Janeiro S.A
Rio de Janeiro, Brazil, 22250-905
4
Beneficência Portuguesa de São Paulo - Real Benemerita Associação Portuguesa de Beneficência
São Paulo, Brazil, 01321-001