Status:
RECRUITING
Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
Lead Sponsor:
Central Institute of Mental Health, Mannheim
Conditions:
Alcohol Use Disorder
Stress Reaction
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The goal of this observational study is to investigate longitudinal stress response profiles and adaptive versus non-adaptive stress responses in alcohol use disorder. The main questions the projects ...
Detailed Description
The main objective of the study is to identify longitudinal profiles and models of adaptive stress responses and stress resilience in individuals with alcohol use disorder (AUD) and understand how str...
Eligibility Criteria
Inclusion
- Inclusion criteria are:
- age between 16 and 65 years
- meeting at least 2 criteria of an alcohol use disorder according to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) (DSM-5), yet without the need for a therapeutic intervention
- fluency in German
- able to understand the study procedures and give informed consent
- willingness to use a study smartphone
- Exclusion criteria are:
- current use of drugs or medications that interact with the central nervous system or the glucocorticoid system
- contraindications for magnetic resonance imaging
- medical history of bipolar disorder, psychotic disorder, schizophrenia or schizophrenic spectrum disorder, or substance use disorder other than alcohol, nicotine, or cannabis
- medical history of severe head injury or other severe central nervous system disorders or other severe somatic disorders (e.g. liver cirrhosis)
- pregnancy
Exclusion
Key Trial Info
Start Date :
December 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06105853
Start Date
December 1 2023
End Date
June 30 2027
Last Update
April 29 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Central Institute of Mental Health
Mannheim, Baden-Wurttemberg, Germany, 68159
2
Central Institute of Mental Health
Mannheim, Germany, 68159