Status:
UNKNOWN
Clinical Feasibility of Brain Radiotherapy Using Synthetic CTs in an MRI-only Workflow
Lead Sponsor:
University of Erlangen-Nürnberg Medical School
Conditions:
Brain Tumor, Primary
Brain Tumor - Metastatic
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this observational study is to show the feasibility of an MRI-only workflow in brain radiotherapy. The main question it aims to answer is: * Is an MRI-only workflow based on deep learning...
Detailed Description
The purpose of this clinical study is to investigate the clinical feasibility of a deep learning-based MRI-only workflow for brain radiotherapy, that eliminates the registration uncertainty through ca...
Eligibility Criteria
Inclusion
- Written informed consent
- Patient older than 18 years
- Tumor or metastases in the brain
- Immobilization with stereotactic mask
- Treatment on stereotactic linear accelerator (2.5 mm leafs) equipped with 2D/2D X-ray system
Exclusion
- Metal in the body, metal implants, pacemakers or other patient-specific factors that are a contraindication to an MRI scan
- Metal implants, pacemakers or other patient-specific factors associated with increased risk from an MRI scan
- Renal insufficiency (eGFR \< 60 ml/min), allergy or other patient-specific factors that constitute a contraindication to contrast administration
- Renal insufficiency (eGFR \< 60 ml/min), allergy or other patient-specific factors associated with an increased risk from contrast administration
- Patients who are institutionalized in care facilities, prisons or other supervised facilities.
- Patients under guardianship
- Non-consenting patients
- Pregnant or breastfeeding patients
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2025
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT06106997
Start Date
January 1 2024
End Date
August 1 2025
Last Update
October 30 2023
Active Locations (1)
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1
Erlangen, Universitätsklinikum Strahlenklinik
Erlangen, Germany, 91054