Status:
UNKNOWN
Hematological Effects of Atypical Antipsychotics (AAPs) in a Geriatric Population: What is the Role of 5-HT2 Receptors
Lead Sponsor:
University Hospital, Strasbourg, France
Conditions:
Neutropenia
Eligibility:
All Genders
65+ years
Brief Summary
White lineage abnormalities and in particular neutropenia and agranulocytosis are known and increasingly studied adverse effects of antipsychotics, particularly second generation. White lineage abnorm...
Detailed Description
The investigators chose as their study population an elderly to very elderly population, hospitalized or residing in the Geriatrics center of a university hospital. Indeed, apart from resistant schizo...
Eligibility Criteria
Inclusion
- Major subject (≥ 65 years old)
- Subject hospitalized in Geriatric Internal Medicine, in Geriatric Follow-up Care and Rehabilitation, in a Long-Term Care Unit or Important Medical-Technical Care, in a Reinforced Accommodation Unit or in a Cognitive-Behavioral Unit at Strasbourg University Hospitals)
- Subject not opposing the reuse of their data for the purposes of this research.
- Indication for the introduction of the neuroleptic indicated
- Available dosage and frequency of administration and duration of treatment
Exclusion
- Subject having expressed opposition to participating in the study
- Presence of a neuroleptic before admission to the University Hospitals of Strasbourg, excluding readmission of a patient included
- Neuroleptics not present on the discharge prescription for long-term treatment
- Neuroleptics prescribed for less than 48 hours
- Presence of a white lineage anomaly prior to the initiation of neuroleptic treatment
- Patient contraindicated for taking a long-term neuroleptic.
- Hematological disease with white lineage abnormality (lymphoma, leukemia, myelodysplasia, mye syndrome
Key Trial Info
Start Date :
March 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 23 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06107322
Start Date
March 1 2023
End Date
March 23 2024
Last Update
October 30 2023
Active Locations (1)
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1
Service de Pharmacie - Stérilisation - CHU de Strasbourg - France
Strasbourg, France, 67091