Status:
UNKNOWN
Impact of Lipodystrophy on the Inflammatory State of Non-diabetic Dunnigan Reunion Island Subjects
Lead Sponsor:
Centre Hospitalier Universitaire de la Réunion
Conditions:
Lipodystrophy
Dunnigan Syndrome
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Few data and small numbers affect the inflammatory profile of Dunnigan patients. The levels of certain pro-inflammatory biomarkers would be found higher in these subjects compared to control individua...
Eligibility Criteria
Inclusion
- Adult subject (\>18 years old) affected by partial Dunnigan lipodystrophy in the homozygous or heterozygous state (genetic search for the positive mutation carried out before inclusion in the study).
- Person affiliated to or beneficiary of a social security scheme.
- Free, informed and written consent signed by the participant and the investigator.
Exclusion
- \- Minor
- Persons placed under judicial protection, person participating in another research including a period of exclusion still in progress, severely impaired physical and/or psychological health, which, according to the investigator, may affect the participant's compliance with the study
- Previous known diabetes
- Pregnant woman
- Woman who gave birth less than 6 months ago
- Breastfeeding in progress
- Participation in other research that may have an impact on the evaluation of the main judgment criteria
- Hemoglobin b level \< 7 mg/dl or \< 9-10 mg/dl for patients with cardiovascular or respiratory pathology.
- Proven inflammatory pathologies
- Anti-inflammatory treatment: taking corticosteroids in the last 3 months.
- Active smoking
Key Trial Info
Start Date :
August 14 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 13 2025
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06107439
Start Date
August 14 2023
End Date
August 13 2025
Last Update
October 30 2023
Active Locations (1)
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1
CHU La Réunion DRCI
Saint-Pierre, Reunion, 97400