Status:

UNKNOWN

Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris

Lead Sponsor:

Chang Gung Memorial Hospital

Conditions:

Acne Vulgaris

Eligibility:

All Genders

20-50 years

Phase:

PHASE1

PHASE2

Brief Summary

Patients with acne vulgaris (AV) appeared to be a chronic inflammation with a wide range in teenagers and adult. The protocol design is as follows. The subjects enrolled through inclusion and exclusi...

Detailed Description

1. Background 1.1 Overview of disease pathogenesis, epidemiology and current treatments Patients with acne vulgaris (AV) appeared to be a chronic inflammation with a wide range in teenagers and adult....

Eligibility Criteria

Inclusion

  • Gender: both
  • Age limit: 20\~50 year/old
  • Acne vulgaris: mild to moderate degree (Investigator's Global Assessment Scale:2\~3)

Exclusion

  • pregnant or breast feeding woman
  • allergic to minoxidil or any ingredient of minoxidil solution including alcohol and propylene glycol
  • deny to discontinue topical therapy of acne more than 7 days before starting treatment
  • deny to discontinue systemic therapy of acne more than 28 days before starting treatment
  • alopecia under or ever using minoxidil, known androgen-AR pathway blocker
  • using shampoo containing minoxidil component in 28 days before starting treatment
  • irregular menstruation of known case of polycystic ovarian syndrome
  • Have had a facial procedure 2 weeks before the study start
  • using any oral contraceptives that have a specific anti-androgenic action 12 weeks before the study start

Key Trial Info

Start Date :

July 11 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2023

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT06108193

Start Date

July 11 2023

End Date

December 31 2023

Last Update

November 3 2023

Active Locations (1)

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1

Linkou Chang Gung Memorial Hospital

Taoyuan District, Taiwan, 333