Status:
RECRUITING
Impact of Negative Pressure Ventilation in Patients Hospitalized with Acute Hypercapnic Respiratory Failure
Lead Sponsor:
University of Missouri-Columbia
Collaborating Sponsors:
Hayek Medical
Conditions:
Acute Hypercapnic Respiratory Failure
Eligibility:
All Genders
21-90 years
Phase:
NA
Brief Summary
The study aims to find if using a Biphasic Cuirass Ventilation is as effective as using a Non invasive Positive Pressure Ventilation in patients admitted with acute hypercapnic respiratory failure.
Detailed Description
Patients presenting via Emergency Room or inpatients who are noted to be in acute hypercapnic respiratory failure will be approached for consent and if they are agreeable will be randomized to the sta...
Eligibility Criteria
Inclusion
- admission diagnosis of hypercapnic respiratory failure
- pH between 7.20-7.35 in an ABG sample or pH between 7.16-.31 in a venous sample.
Exclusion
- age \<21
- Pregnant
- Inmate/Prisoner
- Contraindication for cuirass ventilator (open chest wound, flail chest, prior thoracic surgery)
- Chest wall defect, neuromuscular disease or diaphragmatic paralysis.
- BMI \>50
Key Trial Info
Start Date :
April 3 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2025
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06108284
Start Date
April 3 2024
End Date
October 1 2025
Last Update
October 24 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Missouri Hospitals
Columbia, Missouri, United States, 65212