Status:

UNKNOWN

Dexmedetomidine Effect on Delirium of Elderly Patients

Lead Sponsor:

Assiut University

Conditions:

Delirium in Old Age

Eligibility:

All Genders

60+ years

Phase:

PHASE4

Brief Summary

The Effect of Dexmedetomidine on the Incidence of Delirium Incidence of Post-operative Delirium in Elderly Patients Undergoing Emergency Laparotomy

Detailed Description

Delirium is an acute brain illness, which involves changes in consciousness, attention, cognition, and perception. Delirium is a common postoperative complication, especially in older patients, and is...

Eligibility Criteria

Inclusion

  • • Patients aged 60 years or older of either gender.
  • Patient undergoing emergency laparotomy either trauma or non-trauma patients.

Exclusion

  • • Patients unable to provide written consent.
  • Patients less than 60 years.
  • Known drug intolerance or allergy to dexmedetomidine.
  • Patients previously diagnosed to suffer from major neurocognitive disorder, defined by a mini-mental state examination (MMSE) score \< 24.
  • Severe audiovisual impairment.
  • Child C chronic liver disease.
  • Traumatic brain injury.
  • Intracranial bleeding \< 1y.
  • Psychiatric illness.
  • History of alcohol or drug abuse.
  • Preoperative cerebrovascular accident with residual neurological deficit.

Key Trial Info

Start Date :

November 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 31 2025

Estimated Enrollment :

86 Patients enrolled

Trial Details

Trial ID

NCT06111300

Start Date

November 1 2023

End Date

October 31 2025

Last Update

November 1 2023

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