Status:

RECRUITING

Optimized Diagnosis and Precision Medicine of MODY

Lead Sponsor:

Taichung Veterans General Hospital

Collaborating Sponsors:

National Health Research Institutes, Taiwan

Conditions:

Maturity-Onset Diabetes of the Young (MODY)

Type 2 Diabetes

Eligibility:

All Genders

18+ years

Brief Summary

The goal of this observation is to establish a complete registry for the clinical manifestations, environment, genetic, and other related gene variation information of young-onset diabetic patients. M...

Detailed Description

Diabetes and its complications rank among the top ten death causes in Taiwan. In Taiwan, besides the high prevalence, diabetes also shows a trend in younger people. Compared with type 2 diabetes which...

Eligibility Criteria

Inclusion

  • Case Group Diagnosis of diabetes at or before 25 years of age. BMI (Body Mass Index) of 25 kg/m² or lower. Having at least one parent diagnosed with type 2 diabetes.
  • Family Group Direct blood relatives of the case group, including brothers and sisters of the case group, who have contacted the research team through the subjects.
  • Expressing willingness to participate in this study after granting informed consent.
  • Control Group Diagnosis of diabetes occurred at or before the age of 40, and the individual lacks typical MODY (Maturity-Onset Diabetes of the Young) characteristics.
  • At least one parent has been diagnosed with type 2 diabetes.

Exclusion

  • Confirmed Diagnosed with type 1 diabetes.
  • Under 18 years of age.
  • Unable to personally provide informed consent.
  • Patients with unrelieved leukemia.
  • Patients who have undergone chemotherapy or radiation therapy for cancer within the last 12 months.
  • Cases that have received a blood transfusion within the last six months.
  • Unwilling or unable to continue treatment follow-up at this hospital.

Key Trial Info

Start Date :

May 22 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 21 2028

Estimated Enrollment :

1500 Patients enrolled

Trial Details

Trial ID

NCT06111833

Start Date

May 22 2023

End Date

May 21 2028

Last Update

November 1 2023

Active Locations (1)

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Taichung veterans general hospital

Taichung, Taiwan, 407