Status:
RECRUITING
The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA
Lead Sponsor:
Damascus University
Conditions:
Arthritis Knee
Pain
Eligibility:
All Genders
50-85 years
Phase:
NA
Brief Summary
This interventional study aims to compare the effectiveness of local multimodal drug periarticular injection in TKA patients with the standard pain control regime that includes opioids, NSAIDs, and ot...
Detailed Description
The best pain control regime following TKA is controversial. While opioids have an excellent analgesic effect, they also have many side effects. The investigators are conducting a randomized controlle...
Eligibility Criteria
Inclusion
- all patients with end-stage arthritis of the knee going primary unilateral total knee arthroplasty.
Exclusion
- inflammatory and secondary arthritis of the knee.
- Patients who are allergic to one or more of the drugs used in the injections.
- Patients who are already taking opioids for whatever reason or have a history of addiction.
- BMI less than 20 and more than 35.
- patients with intra-operative complications that would affect the outcomes measurement.
- Patients who are going through complex primary or revision TKA.
- Pregnancy, renal or liver failure.
- Patients who are classified as grade 3 or more according to ASA.
Key Trial Info
Start Date :
March 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 30 2025
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06112548
Start Date
March 1 2024
End Date
November 30 2025
Last Update
May 2 2024
Active Locations (1)
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1
Damascus university
Damascus, Syria