Status:
RECRUITING
Non-invasive Coronary Thrombus Imaging to Define These Cause of Acute Myocardial Infarction
Lead Sponsor:
University of Edinburgh
Conditions:
Myocardial Infarction
Thrombosis
Eligibility:
All Genders
18+ years
Brief Summary
We now have very sensitive blood tests that can pick up damage to the heart and find patients who have had a heart attack. However, whilst this is welcome, it does not identify what causes the heart a...
Detailed Description
1.1 BACKGROUND 1.1.1 Background of coronary artery disease and acute myocardial infarction Coronary artery disease remains the leading cause of death worldwide, with more than 23 million annual deat...
Eligibility Criteria
Inclusion
- Males and females ≥ 18 years of age
- Clinical presentation of chest pain, ST-segment deviation within a coronary artery territory on the electrocardiogram, raised cardiac troponin and non-obstructive coronary arteries on invasive coronary angiography as per international societal diagnostic criteria
Exclusion
- \<18 years of age
- Takatsubo cardiomyopathy
- Myocarditis
- Renal failure (estimated glomerular filtration rate \<30 mL/min/1.73 m2)
- Woman of child-bearing potential who are pregnant or breastfeeding
- Known allergy or contraindication to iodinated contrast or radiotracer
- Patients unable to tolerate the supine position
- Patients unable to provide informed consent
Key Trial Info
Start Date :
January 6 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2028
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06113510
Start Date
January 6 2025
End Date
April 1 2028
Last Update
March 14 2025
Active Locations (1)
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1
Royal Infirmary of Edinburgh
Edinburgh, United Kingdom, EH16 4SA