Status:
UNKNOWN
Viable Myocardium Detected by Hybrid PET/MR and SPECT for the Prediction of the Efficacy of PCI in Patients With CTO.
Lead Sponsor:
The First Affiliated Hospital with Nanjing Medical University
Conditions:
Chronic Total Occlusion of Coronary Artery
Eligibility:
All Genders
18-75 years
Brief Summary
CTO intervention is controversial, and viable myocardium is critical to the improvement of cardiac function and prognosis of patients. However, it remains uncertain whether viable myocardium detected ...
Detailed Description
Percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) represents a major challenge in interventional cardiology. However, the results of the current large-scale CTO study showed t...
Eligibility Criteria
Inclusion
- Age ≧ 18 years, \< 75 years;
- complete occlusion of the coronary artery, confirmed by coronary angiography with TIMI flow grade 0, and occlusion for ≥3 months;
- presence of angina or angina-equivalent symptoms ; undergo coronary intervention;
Exclusion
- life expectancy \< 1 year due to non-cardiac disease;
- contraindications to SPECT/PET/MRI: pregnancy, contrast allergy, claustrophobia, history of pacemaker and ICD implantation, other ferromagnetic materials in the body;
- acute coronary syndrome within the last 3 months;
- severe valvular heart disease;
- haemodynamic instability;
- hepatic or renal insufficiency, with alanine aminotransferase (ALT) \> 3 times the upper limit of normal or glomerular filtration rate ≤ 30 mL/min;
- two or more CTO lesions;
- previous myocardial infarction.
- Others who, in the opinion o f the investigator, should not be enrolled;
Key Trial Info
Start Date :
February 22 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 30 2025
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06113835
Start Date
February 22 2023
End Date
March 30 2025
Last Update
November 2 2023
Active Locations (1)
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1
First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China, 210029