Status:
RECRUITING
Microbiome and Host Susceptibility in Severe Pneumonia, a Prospective, Multicenter, Cohort Study
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Conditions:
Severe Pneumonia
Eligibility:
All Genders
18+ years
Brief Summary
This study was a prospective multicenter cohort of severe pneumonia. And by collecting clinical samples to clarify the correlation between lung microbiome, intestinal microbiome, host susceptibility, ...
Detailed Description
The human lung and intestinal microbiota play an important role in human health. At present, the correlation between lung and intestinal microbiota in severe pneumonia patients and host susceptibility...
Eligibility Criteria
Inclusion
- 1\. New lung infection that meets one of the following definitions: the patient receives mechanical ventilation (invasive or non-invasive) due to acute respiratory failure, with a PEEP level of 5cm or above; Patients receiving high flow oxygen therapy with a FiO2 of 50% or more and a PaO2: FiO2 ratio below 300
Exclusion
- Expected length of stay in ICU is less than 1 day
- Pregnant
Key Trial Info
Start Date :
September 25 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT06114784
Start Date
September 25 2023
End Date
December 31 2026
Last Update
August 7 2025
Active Locations (15)
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1
First Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
2
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
3
Shulan (Hangzhou) hospital
Hangzhou, China
4
Tongde Hospital of Zhejiang Province
Hangzhou, China